Process Drug-Target Interactions
Usage
process_drug_target_interactions(
drug_target_interactions,
PIN_genes,
drug_name_col = "drug_name",
target_col = "gene_name"
)
Arguments
- drug_target_interactions
data frame containing drugs and target genes
- PIN_genes
gene symbols for the chosen PIN
- drug_name_col
name of the column containing drug names (default = "drug_name")
- target_col
name of the column containing drug targets (default = "converted_target_gene")
Value
processed drug-target interactions. Processing involves converting
symbols missing in the PIN, merging drugs that have the same target gene(s)