Example Cohort-level Features Table for Driver Prioritization

The example dataset containing features for prioritizing cancer driver genes for 10 randomly selected samples from TCGA's LAML (Acute Myeloid Leukemia) cohort

example_cohort_features_table

Format

A data frame with 349 rows and 27 variables:

gene_symbol: HGNC gene symbol
metaprediction_score: the maximum metapredictor (coding) impact score for the gene
noncoding_score: the maximum non-coding PHRED-scaled CADD score for the gene
scna_score: SCNA proxy score. SCNA density (SCNA/Mb) of the minimal common region (MCR) in which the gene is located
hotspot_double_hit: boolean indicating whether the gene is a hotspot gene (indication of oncogenes) or subject to double-hit (indication of tumor-suppressor genes)
phenolyzer_score: 'phenolyzer' score for the gene
hsa03320: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04010: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04020: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04024: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04060: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04066: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04110: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04115: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04150: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04151: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04210: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04310: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04330: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04340: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04350: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04370: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04510: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04512: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04520: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04630: boolean indicating whether or not the gene takes part in this KEGG pathway
hsa04915: boolean indicating whether or not the gene takes part in this KEGG pathway

Format

See also